Bipolar disorder: Trimodal age‐at‐onset distribution

Bipolar Disorder 3 Treatment of bipolar disorder

We review recent developments in the acute and long-term treatment of bipolar disorder and identify promising future routes to therapeutic innovation. Overall, advances in drug treatment remain quite modest. Antipsychotic drugs are effective in the acute treatment of mania; their efficacy in the treatment of depression is variable with the clearest evidence for quetiapine. Despite their widespr...

Bipolar Disorder

Bipolar disorder

Bipolar disorder's unique combination of three characteristics - clear genetic diathesis, distinctive clinical features, early availability of an effective treatment (lithium) - explains its special place in the history of psychiatry and its contribution to the current explosive growth of neuroscience. This article looks at the state of the art in bipolar disorder from the vantage point of: (i)...

Bipolar disorder.

INTRODUCTION Bipolar disorder, with mood swings between depression and mania, may affect up to 1.5% of adults, and increases the risk of suicide and disability. Most people improve over time, but two thirds may have residual dysfunction, and at least 40% may have recurrent episodes. METHODS AND OUTCOMES We conducted a systematic review and aimed to answer the following clinical questions: Wha...

Bipolar Disorder

Parris Kidd, PhD – University of California, Berkeley, PhD in cell biology; contributing editor, Alternative Medicine Review; health educator; biomedical consultant to the dietary supplement industry. Correspondence address: 847 Elm Street, El Cerrito, CA 94530 Abstract Bipolar disorder (BD) is characterized by periods of abnormally elevated mood (mania) that cycle with abnormally lowered mood ...